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- Investigational
- • Adjuvant chemotherapy clinical trials of various combinations including 5-FU and leucovorin or
- chemoimmunotherapy with 5-FU and levamisole .
- • Evaluation of the combination of 5-FU + levamisole for Stage II (Dukes' B2) patients will need another one or
- two years of study to determine its effectiveness. The number of patients treated so far with the combination
- has been too low to provide a final answer.
- • 5-FU + PALA (an immune adjuvant drug) or 5-FU and leucovorin may be given for one year after surgery.
- • Postoperative local radiation therapy may help control tumors that have spread to tissues adjacent to the colon
- or lesions in the pelvis.
-